【摘要】 目的总结难治性心脏起搏器相关感染的临床表现和外科处理经验,以提高此类感染的治愈率。方法分析北京大学人民医院收治的难治性起搏器相关感染病例住院及随访资料。难治性感染是指经清创术后复发,经久不愈;心腔内感染;合并其他并发症。结果13年共收治17例,其中13例局部感染,4例感染性心内膜炎,经综合治疗及外科处理,甚至开胸取出电极导线,17例均治愈出院。结论难治性起搏器相关感染正确的外科干预十分重要,包括局部清创、彻底去除起搏系统,甚至心脏直视手术。更多还原

【Abstract】 Objective To describe the clinical manifestation and therapy experiences of permanent pacemaker related refractory infection. Methods We reviewed all the refractory cases of infection involving permanent pacemaker among patients presenting to Peking University People’s Hospital during the past 13 years. Results There were 17 cases of permanent pacemaker related refractory infection. 13 local infections and 4 endocarditis. All patients were cured by a combined approach of complete hardware removal and parenteral antibiotics. Conclusion To cure refractory infection related permanent pacemaker,surgical intervene is mandatory. debridement thoroughly,removing all the pacemaker system and combination use of antibiotics can cure almost all the cases. Though,open-heart surgery is obligated occasionaly.更多还原