【摘要】 目的:探讨辛伐他汀对血脂正常的急性冠脉综合征(ACS)患者冠脉病变炎症的影响。方法:将98例ACS患者随机分为辛伐他汀治疗组(观察组)49例和常规治疗组(对照组)49例,另设健康组49例,测定治疗前、治疗后8周血清超C反应蛋白(hs-CRP)的变化。结果:98例ACS患者的hs-CRP水平均显著高于健康组;对照组治疗8周后,hs-CRP与治疗前相比差异有统计学意义(P<0.05),而观察组经辛伐他汀8周治疗后,hs-CRP与治疗前相比差异有统计学意义(P<0.01)。结论:辛伐他汀对ACS患者的炎症反应有明显的抑制作用。更多还原

【Abstract】 Objective:To investigate the effect of simvastatin on blood lipids of normal acute coronary syndrome(ACS) in patients with coronary artery inflammation.Methods:98 cases of ACS patients were randomly divided into simvastatin treatment group(observation group),49 cases of conventional therapy group(control group) and a separate group of 49 cases of health.To measure changes of hs-CRP before treatment,8 weeks after treatment.Results:98 cases of ACS patients with hs-CRP were significantly higher than the healthy group;8 weeks after treatment,hs-CRP of the control group compared with the pre-treatment differences were significant(P<0.05),while hs-CRP of observation group compared with the pre-treatment differences were significant(P<0.01).Conclusion:The simvastatin on the inflammatory response of ACS patients has significantly restraining effect.更多还原