【摘要】 目的:观察急性心肌梗死(AMI)患者血浆超敏C-反应蛋白(hs-CRP)和尿酸(UA)表达的变化,探讨其临床意义。方法:分别测定46例AMI患者血浆hs-CRP、UA水平,静态12导联同步心电图记录测定QT离散度(QTd)。结果:AMI患者hs-CRP和UA明显高于正常对照(P<0.01),其中合并2型糖尿病,者hs-CRP和UA高于单纯AMI组(P<0.05)。hs-CRP,UA水平均与QTd相关(P<0.01,P<0.05)。结论:血尿酸和超敏CRP与急性心肌梗死的发生发展密切相关,检测血浆hs-CRP和UA有助于对AMI的早期诊断和预后评估。更多还原

【Abstract】 Objective:To investigate the relationship among serum uric acid (UA), hs-CRP and acute myocardial infarction (AMI). Methods:The serum UA and hs-CRP level were detected in 46 AMI patients which including 16 cases accompanied by type 2 diabetes mellitus(2DM).46 normal cases were taken as control. The change of QT dispersion(QTd) of ECG were measured in AMI groups after 1 week. Results:Serum UA and hs-CRP levels in AMI groups were significantly higher than those in control group (P<0.01). Serum UA and hs-CRP levels in group accompanied with 2DM were obviously higher than those in group with AMI only(P<0.05). The UA and hs-CRP were highly relative with QTd, respectively(P<0.05, P<0.01).Conclusion:The UA and HS-CRP levels have close relation with AMI and increase along with the severity of post-discharge cardiovascular events in patients with AMI.更多还原