妊娠期高血压疾病患者肾功能监测的临床意义

【摘要】 目的:通过检测血清尿素氮(Bun)、肌酐(Cr)及尿酸(UA),探讨妊娠高血压疾病的肾功能改变情况及肾功能损害对胎儿的影响。方法:采用全自动生化分析仪,分别对72例妊娠高血压疾病患者(研究组)及74例正常孕妇(对照组)测定Bun、Cr及UA,并跟踪肾功能改变对胎儿的影响。结果:妊娠高血压疾病Bun、Cr及UA异常的发生率分别为48.6%、44.4%及61.1%;Bun、Cr及UA异常导致胎儿宫内窘迫的发生率分别为62.9%、75.0%及56.8%。两组统计学比较差异具有显著性(P<0.05)。结论:Bun、Cr及UA的检测,是诊断妊娠高血压疾病肾功能损害的三项敏感指标,胎儿窘迫的发生与孕妇肾功能损害关系密切。更多还原

【Abstract】 Objective:To explore the effects of the changes and lesions of renal function on the fetus,serum urea nitrogen (Bun),creat- inine (Cr) and uric acid (UA) were detec- ted in the patients with gestational hyperten- sion.Methods:Bun,Cr and UA in serum from 72 patients diagnosed the gestational hypertension and 74 normal pregnant women were detected by the UAtomatic biochemical analyzer,and the effects on fetus have also been observed by renal function monitoring. Results:The abnormal incidences of Bun,Cr and UA in the patients with gestational hy- pertension were 48.6%,44.4% and 61.1%,and the incidences of fetal distress cUAsed by Bun,Cr and UA abnormality were 62.9%,75.0% and 56.8% respec- tively.Conclusions:Bun,Cr and UA were three sensitive indicators to diagnose the re- nal function lesion in gestational hyperten- sion,and there was an intimate relation be- tween the occurrence of fetal distress and re- nal function lesion in the pregnant women.更多还原