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经气管镜腔内射频联合放疗治疗中心型非小细胞肺癌疗效分析

The treatment of centrally located non-small cell lung cancer by electrobronchoscopic radiofrequency

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【作者】 张铭张全卯李杰李慧娟王峰郭斌

【Author】 ZHANG Ming1,ZHANG Quan-mao1,LI Jie2,LI Huijuan1,WANG feng1,GUO Bin1(1.Department of Endoscopy,2.Department of Thoracic Radiotherapy,Shanxi Tumor Hospital,Taiyuan,Shanxi 030013,P.R.China)

【机构】 山西省肿瘤医院内窥镜科山西省肿瘤医院放胸科

【摘要】 目的评价气管镜腔内射频加局部放疗与单纯局部放疗的疗效对比。方法对130例晚期中心型非小细胞肺癌患者进行射频加局部放疗与单纯局部放疗。采用射频加局部放疗组65例,局部单纯放疗65例。放疗结束后观察气促症状缓解率。结果射频加放疗组65例,放疗结束后气促症状缓解率(显效+有效)为96.9%(63/65),单纯局部放疗组为76.9%(50/65),两组相比有统计学差异(P<0.05)。结论射频加局部放疗与单纯局部放疗两种方法均有效。射频加局部放疗优于单用局部放疗。

【Abstract】 【Objective】To investigate the value of electrobronchoscopic radiofrequency in the treatment of centrally located non-small cell lung cancer(NSCLC).【Methods】A total of 130 cases with centrally located NSCLC were equally divided into a groups with 65 in each.Both radiofrequency treatment and local radiotherapy were performed in radiofrequency group.Only local radiotherapy was performed in radiotherapy group.The rate of dyspnea alleviation was observed after radiotherapy,and the efficacy of both therapies was compared.【Results】 The rates of dyspnea alleviation(markedly effective and effective rate) were 96.9%(63/65) in radiofrequency group and 76.9%(50/65) in radiotherapy group with statistic difference(P <0.05).【Conclusion】Both electrobronchoscopic radiofrequency treatment and solely radiotherapy are effective for centrally located NSCLC with the former being more valid and simpler with little injury.Therefore a combination of electrobronchoscopic radiofrequency and local radiotherapy is a better option for the treatment of late-stage centrally located NSCLC.

【基金】 山西省科技厅重点攻关项目基金资助(No:2007031094-2)
  • 【文献出处】 中国内镜杂志 ,China Journal of Endoscopy , 编辑部邮箱 ,2009年12期
  • 【分类号】R734.2
  • 【被引频次】1
  • 【下载频次】45
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