节点文献

子宫恶性肿瘤患者腹腔镜与开腹淋巴结清扫术后近期生存质量的比较

A prospective comparison of quality of life between laparoscopic and laparotomic approaches in patients with uterine malignancies

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 颜笑健李光仪尚慧玲林铁成陈露诗郑飞云

【Author】 YAN Xiao-jian1,LI Guang-yi2,SHANG Hui-ling2,LIN Tie-cheng2,CHEN Lu-shi2,ZHENG Fei-yun1(1.Department of Gynecology,the First Affiliated Hospital of Wenzhou Medical College,Wenzhou,Zhejiang 325000,P.R.China;2.Department of Gynecology,the First People’s Hospital of Foshan,Foshan,Guangdong 528000,P.R.China)

【机构】 温州医学院附属第一医院妇科广东省佛山市第一人民医院妇科

【摘要】 目的比较子宫恶性肿瘤患者全腹腔镜广泛全宫加盆腔淋巴结清扫术与开腹手术近期的生存质量。方法2006年1月~2007年1月,43例(宫颈癌33例,内膜癌10例)患者进入前瞻性对照研究,其中腹腔镜组29例,开腹组14例。每例患者术前、术后1周、术后1个月接受EORTCQOL-C30(V3.0)中文版量表调查。结果术前两组生存质量相似,术后1周腹腔镜组PF(躯体功能)下降程度较开腹组低(t=2.382,P=0.022),PA(疼痛)、AP(食欲丧失)症状较开腹组轻(t=-2.626,-2.320,P=0.019,0.030);术后1个月腹腔镜组PA(疼痛)仍较开腹组轻(t=-2.115,P=0.041),而其他各领域两组差异无显著性。术后1周腹腔镜组和开腹组PF(躯体功能)、RF(角色功能)均较术前明显下降,术后1个月较术后1周改善,但仍低于术前,差异有显著性(均P<0.05)。腹腔镜组术后1个月EF(情绪功能)较术前改善(P=0.044)。结论子宫恶性肿瘤腹腔镜组患者术后近期生存质量优于开腹组。

【Abstract】 【Objective】To compare the short-term quality of life(QOL) in patients with uterine malignancies treated by total laparoscopic radical hysterectomy and pelvic lymphadenectomy and by laparotomic approaches.【Methods】 Between January 2006 and January 2007,forty-three patients with uterine malignancies(33 cases of cervical cancer,10 cases of endometrial cancer) were enrolled in a prospective trial design and treated with laparo-scopic(29) or laparotomic(14) approach.In the patients,QOL was evaluated using the EORTC QOL-C30(V3.0) before surgery,1 week and 1 month after surgery.【Results】 Baseline assessments showed EORTC QOL C30 scores were similar in both groups.One week after surgery,in laparoscopic group,the decrease in the scores for physical functioning was significantly slighter(t=2.382,P=0.022),and patients experienced less postoperative pain and anorexia(t=-2.626,-2.320,P=0.019,0.030) than those in laparotomic group.After the surgery,the scores for physical functioning,role functioning in both groups decreased significantly,and improved at 1 month after operation but still were still lower those before treatments.【Conclusions】For uterine malignancies,the laparoscopic approach provides significant benefits compared with laparotomy in terms of QOL.

【基金】 佛山市科技攻关项目立项(200608019);温州市科技项目(Y20080118)
  • 【文献出处】 中国内镜杂志 ,China Journal of Endoscopy , 编辑部邮箱 ,2009年06期
  • 【分类号】R737.33
  • 【被引频次】7
  • 【下载频次】182
节点文献中: 

本文链接的文献网络图示:

本文的引文网络