【摘要】 目的:探讨沙参麦冬汤对运动小鼠免疫功能的影响。方法:40只雄性昆明种小鼠,随机分为4组:安静对照组、运动对照组、运动+小剂量沙参麦冬汤组、运动+大剂量沙参麦冬汤组,运动小鼠递增负荷游泳训练40d,游泳时间由40min开始渐增至100min,第40天游泳至力竭,24h后处死取血。测定小鼠免疫器官脏器/体重比值、外周血免疫球蛋白、外周血T细胞亚群。结果:服药组小鼠脾指数、外周血IgG、IgA、CD4+T细胞百分比、CD4+/CD8+比值均显著高于运动对照组(P<0.01或P<0.05);大剂量组小鼠胸腺指数、血清IgM值显著高于运动对照组(P<0.05)。结论:沙参麦冬汤具有提高大强度耐力训练小鼠免疫力的作用。更多还原

【Abstract】 Objective:To study the effect of Radix Ophiopogon soup on the immune function fo exercises mice.Method:Forty male Kunming mice were randomly divided into 4 groups:quiet control group,exercises control group,exercises + Radix Ophiopogon soup of low-dose group,exercises + Radix Ophiopogon soup of high-dose group.The exercises mice swam with progressively increased load for 40d,Twenty-four h after the last exhaustive swimming,the mice were sacrificed.The changes of immune organs/body weight ratio,the peripheral blood immunoglobulin,and peripheral blood T lymphocytes subsets of mice were determined.Result:Spleen index,peripheral blood IgG,IgA,CD4+T cells percentage and CD4+/CD8+ ratio in two drug groups were significantly higher than that in exercises group(P<0.01 or P<0.05);Hymus index,serum IgM of high-dose group were significantly higher than that in exercises group(P<0.05).Conclusion:Radix Ophiopogon soup could enhance the immunity of mice with strong endurance training.更多还原