【摘要】 目的探讨体检人群高尿酸血症与血致动脉硬化指数(AIP)、非高密度脂蛋白胆固醇(non-HDL-C)水平相关性及意义。方法选择2004年1月~2006年12月在温州医学院附属一院体检中心接受体检者31 707人,测定甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL-C)、高密度脂蛋白胆固醇(HDL-C)、尿酸(UA),计算non-HDL-C和AIP;并按尿酸水平高低进行分组比较。结果男性UA、TG、TC、non-HDL-C、AIP水平均明显高于女性(均P<0.01),而HDL-C水平则低于女性(P<0.01);男性高尿酸组AIP、non-HDL-C水平明显高于正常尿酸组,而HDL水平降低;女性高尿酸组的TG、TC、AIP、non-HDL-C水平明显高于正常尿酸组,HDL水平降低;UA与non-HDL-C、AIP、TG、TC水平呈正相关,与HDL-C呈负相关。结论尿酸水平有明显性别差异,高尿酸血症人群存在心脑血管疾病的多种危险因素,应该引起重视。更多还原

【Abstract】 Objective To analyze the correlation between hyperuricemia and non-high density lipoprotein cholesterol(non-HDL-C) and atherogenic index of plasma(AIP) in a normal population.MethodsThe 31707 people were studied in a health examination from 2004 to 2007.The blood samples from the subjects were detected for uric acid(UA),TG,TCH,HDL and the AIP,non-HDL-C were calculated.ResultsThe concentrations of UA,non-HDL-C for the men was higher than that of the women,and gradually increased with the age.Compared with the normal UA group,the AIP and non-HDL-C were elevated.The UA was positively correlated with the AIP,non-HDL-C and was negatively correlated with the HDL-C.ConclusionThe concentration of UA was different among male and female.The hyperuricemia population is at high risk of heart and cerebral disease and more attention should be paid to the population.更多还原