【摘要】 精原干细胞(spermatogonial stem cells,SSCs)是维持精子发生的一类干细胞,由于与人亲缘关系的相近性,使得开展非人灵长类动物SSCs研究具有重要的理论意义和比较医学价值。本文综述了非人灵长类动物SSCs的生物学特性、鉴定方法、冷冻保存、移植及生精细胞缺失模型建立等方面的研究进展。更多还原

【Abstract】 Spermatogonial stem cells(SSCs) initiate and maintain the continuous supply of sperms in mammals.Because Non-human primates have very similar spermatogenesis process and other biological characteristics compared with human,studying SSCs in these animals had important theoretical and comparative medicine value.Here we review SSCs’ biological characteristic,characterization method,cryopreservation,transplantation and germ cell depletion model in non-human primates.更多还原