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孕期感染弓形虫的妊娠结局及存活儿的随访观察

Follow up and observation on effect of toxoplasma gondii infection during pregnancy on pregnant outcomes and live-born infants

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【作者】 苑文英刘秀华于朝云赵盛赵清耿仙唐志远薛娟

【Author】 YUAN Wen-Ying,LIU Xiu-Hua,YU Chao-Yun et al.Department of Parasitology,Medical Board,Hebei University,Baoding 071000,Hebei,China

【机构】 河北大学医学部寄生虫教研室

【摘要】 目的:了解母亲孕期感染弓形虫的妊娠结局及出生活婴的体格、智力发育情况。方法:孕妇按静脉血弓形虫IgM或CAg阳性/阴性分感染组和非感染组,将小儿按脐血弓形虫检测结果分组,观察发育情况。结果:母亲感染组异常妊娠结局高于正常非感染组;孕期感染弓形虫出生子代发育受到明显影响,体重、智力显著降低,但对身高无明显影响。结论:孕期感染弓形虫可以透过胎盘将病原体传给子代,母亲孕期感染弓形虫不仅脐血阳性子代发育指标明显降低,脐血阴性者也低于非感染组。

【Abstract】 Objective:To understand the effect of toxoplasma gondii infection during pregnancy on pregnant outcomes,physical and intellectual development of live-born infants.Methods:The pregmant women and infants were divided into infected group and uninfected group according to their blood results of toxoplasma gondii IgM or CAg,the physical and intellectual development of live-born infants were observed.Results:The incidence of abnormal pregnancy in infected group was higher than that in uninfected group;toxoplasma gondii infection had obvious impact on live-born infants,physical and intellectual development of live-born infants were affected obviously excluding body height.Conclusion:Toxoplasma gondii can be transmitted to descendants by cord blood,and physical and intellectual development of their infants are low.

【基金】 河北省科技厅项目〔09276102D-29〕;河北省卫生厅科技厅项目〔08167〕
  • 【文献出处】 中国妇幼保健 ,Maternal and Child Health Care of China , 编辑部邮箱 ,2009年31期
  • 【分类号】R714.2
  • 【被引频次】1
  • 【下载频次】119
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