【摘要】 目的:探讨窒息新生儿血浆氨基末端脑钠肽前体(NT-proBNP)水平及临床意义。方法:选择用Apgar评分法诊断新生儿窒息,轻度组患儿54例、重度组49例、正常对照组(健康对照组)50例采用化学发光方法分别检测血浆NT-proBNP。结果:窒息组出生3天内血浆NT-proBNP水平显著高于对照组中出生3天内者的水平;重度窒息组血浆NT-proBNP显著高于轻度窒息组,与对照组比较有统计学意义;轻度窒息组血浆NT-proBNP明显高于健康对照组。结论:新生儿窒息血浆中氨基末端脑钠肽前体(NT-proBNP)的水平与新生儿窒息的程度成正比关系。更多还原

【Abstract】 Objective:To explore the plasma N-terminal pro-brain natriuretic peptide(NT-proBNP) level of neonates with neonatal asphyxia and its clinical significance.Methods:Apgar score was used to diagnose neonatal asphyxia,the levels of NT-proBNP in plasma from 54 cases of mild neonatal asphyxia,49 cases of severe neonatal asphyxia and 50 healthy neonates were detected by chemiluminescent method.Results:For the neonates born within 3 days,the level of NT-proBNP in plasma in neonatal asphyxia group was significantly higher than that in control group;and the level of NT-proBNP in plasma in severe neonatal asphyxia group was significantly higher than that in mild neonatal asphyxia group.Conclusion:There is positive correlation between the NT-proBNP level and the degree of neonatal asphyxia.更多还原