【摘要】 目的应用数字减影血管造影(DSA)了解青年缺血性脑卒中脑血管病变的特点。方法选择行DSA检查的青年(年龄15～45岁)缺血性卒中患者42例为观察组,同期行DSA检查的中年(年龄46～64岁)缺血性卒中患者60例为对照组,分析青年患者血管病变的发病特点。结果42例15～45岁患者中有64.3%出现脑血管异常,2例为椎动脉发育较差,4例moyamoya病,3例颅内动脉炎改变,18例血管狭窄和(或)闭塞。60例46～64岁患者中有60.0%出现脑血管异常,2例为椎动脉发育较差,1例moyamoya病,33例血管狭窄和(或)闭塞。15～45岁组患者危险因素中高血压占28.6%(12/42),糖尿病4.8%(2/42),脂代谢异常16.7%(7/42)。而在46～64岁组患者中高血压占58.3%(35/60),糖尿病28.3%(17/60),脂代谢异常30.0%(18/60)。46～64岁组患者中合并高血压和(或)糖尿病较15～45岁组患者更常见,两组差别有统计学意义(P<0.01),脂代谢异常均为两组患者的危险因素,差别无显著差异(P>0.05)。结论高血压、糖尿病在46～64岁组患者中更常见,脂代谢异常均为两组患者的危险因素。15～45岁组患者和46～64岁组脑梗死发病率、DSA异常发生率、血管狭窄和(或)闭塞发生率、mRS评分均无显著差异(P>0.05),行血管造影检查能有效发现青年人缺血性卒中的病因。更多还原

【Abstract】 Objective To investigate the cerebrovascular features in young adults with ischemic cerebrovascular disease.Methods 102 cases(aged from 15 to 64)with ischemic stroke,admitted by head CT/MRI and DSA,were divided into two groups:aged from 15 to 45 group and aged from 46 to 64 group.These data were reviewed retrospectively to determine the classified type and distribution of the cerebrovascular lesions.Results 27 cases in aged from 15 to 45 group(64.3%)were found cerebrovascular lesions.Among them,vertebral artery of 2 cases developed poorly,4 cases had moyamoy disease,3 cases had arteritis,18 cases had vascular stenosis and/or occlusion.36 cases in aged from 46 to 64 group(60.0%)were found cerebrovascular lesions,vertebral artery of 2 cases developed poorly,1 cases was moyamoy disease,33 cases had vascular stenosis and/or occlusion.Risk factors of cerebral infarction in aged from 15 to 45 group were hypertension(28.6%,12/42),diabetes(4.8%,2/42),and abnormal lipid metabolism(16.7%,7/42).Hypertension and diabetes were more frequently in 46 to 64 group(P<0.01),and there was no defference in the abnormal lipid metabolsm between the 2 groups(P>0.05).Conclusion Hypertension and diabetes were more frequently in 46 to 64 group.There was no defference in the incidence of cerebral infarction and cerebrovascular lesions between the 2 groups(P>0.05).DSA can provide the diagnosis and aid in treatment.更多还原