【摘要】 目的研究菝葜Smilax china的化学成分。方法采用硅胶、Sephadex LH-20、ODS柱色谱及半制备液相色谱等技术分离菝葜的化学成分,根据化合物的理化性质及波谱数据鉴定化合物的结构。结果从菝葜中分离得到11个化合物,其中黄酮类成分7个:二氢山柰酚-5-O-β-D-葡萄糖苷(Ⅰ)、黄杞苷(Ⅱ)、异黄杞苷(Ⅲ)、双氢槲皮素-3′-O-葡萄糖苷(Ⅳ)、3,5,7,3′,5′-五羟基二氢黄酮醇(Ⅴ)、落新妇苷(Ⅵ)和槲皮素-3′-O-葡萄糖苷(Ⅶ);二苯乙烯类化合物4个:白藜芦醇昔(Ⅷ)、藨草素A(scirpusin A,Ⅸ)、白藜芦醇(Ⅹ)和2,4,3′,5′-四羟基茋(Ⅺ)。结论化合物Ⅳ～Ⅸ均为首次从该植物中分离得到;化合物Ⅸ的碳谱数据为首次报道。更多还原

【Abstract】 Objective To study the chemical constituents of Smilax china.Methods The compounds were isolated by silica gel,Sephadex LH-20,ODS chromatography,and semi-preparative HPLC.Their structures were elucidated on the basis of MS and NMR spectroscopic analyses.Results Seven flavonoids and four stilbenes were isolated and identified as dihydrokaempferol-5-O-β-D-glucoside（Ⅰ）,engeletin （Ⅱ）,isoengeletin（Ⅲ）,dihydroquercetin-3-O-glycoside（Ⅳ）,3,5,7,3’,5’-pentahydroxy-flavanonol （Ⅴ）,astilbin（Ⅵ）,quercetin-3’-Oglycoside（Ⅶ）,piceid（Ⅷ）,scirpusin A（Ⅸ）,resveratrol（Ⅹ）,and oxyresveratrol（Ⅺ）.Conclusion CompoundsⅣ—Ⅸare isolated from this plant for the first time,among which the ¹³C-NMR data of compoundⅨis reported firstly.更多还原