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白花丹参的化学成分研究(Ⅱ)

Chemical constituents of Salvia miltiorrhiza f. alba

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【作者】 曹春泉孙隆儒王小宁

【Author】 CAO Chun-quan, SUN Long-ru, WANG Xiao-ning(School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China)

【机构】 山东大学药学院

【摘要】 目的研究白花丹参的化学成分。方法采用色谱法分离,波谱学数据分析鉴定结构。结果从白花丹参根的乙醇提取物中分离得到4个化合物,分别鉴定为8,9-dihydro-1,6-dimethylfuro[3,2-c]naphtha[2,1-e]oxepine-10,12-dione(Ⅰ)、丹参二醇C(Ⅱ)、鼠尾草酚酮(Ⅲ)和1,2,6,7,8,9-hexahydro-1,6,6-trimethyl-3,11-dioxanaphtho[2,1-e]azulene-10,12-dione(Ⅳ)。结论化合物Ⅰ为新化合物,命名为白花丹参酮(salmilalba-none),化合物Ⅱ~Ⅳ为首次从白花丹参中分离获得。

【Abstract】 Objective To study the chemical constituents of Salvia miltiorrhiza f. alba Methods The compounds were isolated by chromatographic techniques and their structures were elucidated by spectroscopic analysis. Results Four compounds were obtained from the plant and identified as 8, 9-dihydro-1, 6-dimethylfuro [3, 2-c] naphtha [2, 1-e] oxepine-10, 12-dione (Ⅰ), tanshindiol C (Ⅱ), salviolone (Ⅲ), 1, 2, 6, 7, 8, 9-hexahydro-1, 6, 6-trimethyl-3, 11-dioxanaphtho [2, 1-e] azulene-10, 12-dione (Ⅳ). Conclusion Compound Ⅰ is a new one, named salmilalbanone (8, 9-dihydro-1, 6-dimethylfuro [3, 2-c] naphtha [2, 1-e] oxepine-10, 12-dione), while compounds Ⅱ—Ⅳ are isolated from the plant for the first time.

  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,2009年02期
  • 【分类号】R284.1
  • 【被引频次】21
  • 【下载频次】707
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