【摘要】 目的:建立杨梅素分散片的质量标准。方法:采用紫外光谱和红外光谱对杨梅素分散片进行定性鉴别;采用高效液相色谱法对制剂中杨梅素进行含量测定;并对分散片的溶出度、分散均匀性进行了检查。结果:杨梅素分散片乙醇溶出物的紫外光谱和红外光谱与杨梅素基本一致;HPLC方法学考察显示杨梅素在0.071~0.165 mg/mL范围内峰面积与浓度呈良好线性关系,r=1.000 0,加样回收率为98.55%(n=6),RSD=1.92%;溶出度、分散均匀性均优于普通片。结论:所建立的方法简便易行,重现性好,专属性强,可作为杨梅素分散片的质量控制方法。更多还原

【Abstract】 AIM: To establish quality standard for Myricetin Dispersible Tablets. METHODS: Myricetin Dispersible Tablets were identified by UV and IR,and the content of myricetin in the tablets was determined by HPLC. RESULTS: The UV and IR spectra of Myricetin Dispersible Tablets were similar with those of myricetin.The linear range of myricetin was within the range of 0.071-0.165 mg/mL(r=(1.000 0)).The average recovery was 98.55%(n=6),and the RSD was 1.92%. CONCLUSION: The quality standard developed can be used for the quality control of Myricetin Dispersible Tablets.更多还原