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Th17细胞与皮肤病

Th17 Cells and Skin Diseases

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【作者】 林熙然黄畋

【Author】 LIN Xi-ran~1,HUANG Tian~2 (1 The First Affiliated Hospital of Dalian University,Dalian 116011,China;2 The Second Affiliated Hospital of Dalian University,Dalian 116027,China)

【机构】 大连医科大学附属第一医院大连医科大学附属第二医院

【摘要】 Th17细胞是新近认定的不同于Th1和Th2的特有T细胞系,与其他免疫细胞协调介导各种免疫反应,在一些原来认为由Th1介导的自身免疫性疾病中起重要作用。已有研究证明Th17细胞也介导银屑病的发病,并提示其在一些皮肤病中起作用。

【Abstract】 Th17 cells were identified as a distinct T-cell lineage different from Th1 and Th2 recently,with the function of cooperatively mediate various immunologic responses and playing important roles in autoimmune diseases with other immune cells which were considered to be mediated by Th1 originally.Th17 cells have been demonstrated also to act as a mediator in pathogenesis of psoriasis,and suggested to play roles in certain skin diseases.

【关键词】 Th17细胞皮肤病
【Key words】 Th17 cellsSkin diseases
  • 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,2009年02期
  • 【分类号】R751
  • 【被引频次】19
  • 【下载频次】319
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