【摘要】 目的探讨联合脏器切除治疗进展期胃癌的疗效及指征。方法回顾性分析1995年6月至2008年6月收治侵犯邻近脏器的进展期胃癌62例,其中32例联合脏器根治切除(A组),30例姑息切除(B组),两组病人术后均行同方案化疗、免疫治疗和支持治疗,均未行放疗。结果A、B组术后1、3、5年生存率分别为59.4%、30%;42.5%、0%;21.9%、0%。两组差异均有统计学意义(P<0.05)。A组手术并发症较B组高,但可治愈。结论对侵犯邻近脏器的进展期胃癌,若身体情况允许、能耐受手术者,行联合脏器根治切除治疗可获得较好的疗效,不应放弃。重视围手术期处理及术中术后腹腔化疗,可提高生存率。更多还原

【Abstract】 Objective To explore the significance and effect of combined evisceration for treating advanced gastric cancer.Methods Clinical data of 62 cases of advanced gastric cancer from June 1995 to June 2008 were analyzed retrospectively.Group A included 32 cases treated by combined organ resection,and group B included 30 cases treated by palliative resection.Patients in both groups received same chemotherapy and immunotherapy after surgery,none had radiotherapy.Results The 1-,3-and 5-year survival rate in group A were 59.4%,42.5% and 21.9% respectively,while the rates in group B were 30%,0 and 0 respectively.Differences between the two groups were significant.The surgical complications in group A were more than that in group B but were curable.Conclusion Combined organ resection is practicable for treating advanced gastric cancer.更多还原