【摘要】 目的:观察银杏制剂对颈动脉粥样斑块的临床疗效。方法:选择颈动脉粥样斑块患者80例,随机分为两组。治疗组40例,服用银杏叶滴丸300mg,3次/d;对照组40例,服用肠溶阿司匹林片100mg,1次/d。疗程6个月。治疗前后用彩色多普勒超声检测颈动脉内中膜(IMT)厚度、计算斑块面积、Crouse斑块积分、血流动力学参数。结果:治疗组颈动脉IMT、斑块总积分、斑块面积均有改善,颈动脉血流改善,阻力减少,与对照组相比有统计学差异(P<0.05)。结论:银杏制剂有一定的消减及稳定动脉粥样硬化斑块的作用。更多还原

【Abstract】 Objective:To determine effects of Ginkgo Biloba Extract (GBE) on carotid atherosclerotic plaques.Methods:Eighty patients with carotid atherosclerosis (CAS) were randomly assigned to a therapeutic group and a control group. Forty Patients in the therapeutic group were orally administrated by Ginkgo Leaf Dripping Pills (GLDPs) 300 mg tid while forty patients in the control group were orally administrated by tablet enteric coated aspirin 100 mg qd. The length of treatment course in the two groups was six months. The intima-media thickness (ITM),area of carotid plaques,Crouse integrals,and blood flow parameters of carotid arteries were tested using color Doppler ultrasound imaging before and after treatment.Results:After treatment,the IMT,Crouse integrals,plaque area,and carotid resistance were significantly lower in the therapeutic group than those in the control group (P<0.05). Conclusions:GBE can reduce and stabilize the atherosclerotic plaques.更多还原