【摘要】 背景:青光眼是一种常见的不可逆的致盲性眼病。激光手术为其治疗增加了一条新的途径。目的:为了克服现阶段青光眼传统外科手术的一些弊端和验证CO₂激光巩膜切除联合虹膜切除术的有效性与安全性。材料和方法:用于CO₂激光巩膜切除联合虹膜切除的青光眼激光手术系统,40只成年新西兰大白兔。将40只兔按照随机数字表法分成5组。兔右眼行CO₂激光巩膜切除联合虹膜切除术,兔左眼行传统小梁切除术。结果:术后,激光组前房反应明显小于传统手术组,传统手术组的功能性滤过泡明显减少,术后7到60天,激光组和传统组间的平均眼压存在统计学差异（p<0.05）,激光组在术后的并发症少。对于兔眼CO₂激光巩膜切除联合虹膜切除是安全、易实施且有效的手术方式。更多还原

【Abstract】 Background:Glaucoma is a common eye disease that can lead to irreversible blindness.Laser surgery added a new therapeutic modality.Objective:To cure glaucoma avoiding drawbacks of traditional glaucoma operation,and to study the efficiency and safety of CO₂ laser sclerectomy with iridectomy.Materials and Method:A developed CO₂ glaucoma surgery system for laser sclerectomy with iridectomy was applied.A total of 40 New Zealand white rabbits were recruited.All rabbits were randomly divided into 5 groups.The right eye of each rabbit was treated with CO₂ laser Sclerectomy with Iridectomy,and the left eye was treated with traditional trabeculectomy.Intraocular pressure（IOP）,anterior reflects,filtering bleb and pathology were evaluated.Results:Anterior chamber reaction of laser group was lower than that of traditional surgery group,functional filtering bleb number in traditional surgery group is fewer than laser group..There was significant difference（p<0.05） in posttreatment mean decrease in intraocular pressure（IOP） between the laser group and traditional group from 7th day to 60th day. Compared with the traditional group,fewer complications were found in laser group.CO₂ laser sclerectomy with iridectomy seems to be a safe,easily performed,and effective procedure to rabbit eye.更多还原