【摘要】 目的建立毛细管气相色谱法测定布洛芬片含量。方法将样品用甲醇溶解后滤过,取续滤液直接进样,用SE-30大口径石英毛细管色谱柱(30m×0.53mm,1.0μm)和FID检测器,以咖啡因为内标进行测定。结果布洛芬质量浓度的线性范围为0.1015～1.015mg/mL(r=0.9998),平均回收率为99.58%,RSD为0.56%(n=9),样品含量在97.35%～101.20%范围内。结论所用方法操作简便、快速、准确,可用于布洛芬片的含量测定。更多还原

【Abstract】 Objective To establish a GC method for the analysis of Ibuprofen Tablets.Methods After the sample was dissolved in methyl alcohol and got filtered.The filtrate was analysed directly.The GC system included SE-30 wide bore capillary column(30m×0.53mm,1.0μm)with flame ionization detector(FID),caffeine was used as internal standard.Results The linear range of ibuprofen was 0.101 5-1.015mg/mL(r=0.999 8).The average recovery rate was 99.58%,RSD=0.56%(n=9).The content of Ibuprofen Tablets was between 97.35% and 101.20%.Conclusion This method is simple,quick,accurate and suitable for the assay of Ibuprofen Tablets.更多还原