【摘要】 目的研究经典药对远志-石菖蒲配伍对单味药材指标成分的影响。方法采用高效液相色谱(HPLC)法测定远志、石菖蒲及远志-石菖蒲药对远志皂苷元和α-细辛醚的含量。色谱柱为Shimadzu VP-ODS柱(150mm×4.6mm,5μm);远志皂苷元的流动相为乙腈-0.05%磷酸水溶液(43∶57),检测波长为205nm;α-细辛醚的流动相为乙腈-0.05%磷酸水溶液(52∶48),检测波长为257nm。结果远志、远志-石菖蒲中远志皂苷元含量分别为0.392%和0.297%,石菖蒲、远志-石菖蒲中α-细辛醚含量分别为0.0605%和0.0629%。结论远志-石菖蒲配伍后,药对中远志皂苷元的含量显著降低,而α-细辛醚的含量变化不明显。更多还原

【Abstract】 Objective To research the compatibility regularity of the matched pair of Polygala tenuifolia Willd.and Acorus tatarinowii Schott.Methods The mobile hase of senegenin was acetonitrile-0.05% phosphoric acid(43:57),the detective wavelength was 205nm;the mobile phase of α-asaricin was acetonitrile-0.05% phosphoric acid(52:48),the detective wavelength was 257nm.The flow rate was about 1mL/min,and the Shimadzu VP-ODS(150mm×4.6mm,5μm)column was used.Results The contents of senegenin in Polygala tenuifolia Willd.and the matched pair of Polygala tenuifolia Willd.and Acorus tatarinowii Schott were 0.392% and 0.297% respectively;the contents of α-asaricin in Acorus tatarinowii Schott and the matched pair of Polygala tenuifolia Willd.and Acorus tatarinowii Schott were 0.060 5% and 0.062 9% respectively.Conclusion After the match of Polygala tenuifolia Willd.and Acorus tatarinowii Schott,the content of matched pair was decreased obviously,but there was not obviously change of α-asaricin.更多还原