【摘要】 目的评价国产注射用亚胺培南西司他丁钠(齐佩能)对中重度细菌性感染的临床有效性及安全性。方法采用随机开放、平行对照试验设计,以进口注射用亚胺培南西司他丁钠(泰能)作对照药物。结果齐佩能与泰能的临床有效率分别为86.42%和81.82%,细菌清除率分别为85.71%和87.18%,不良反应发生率为4.94%和3.41%,两组比较均无显著性差异(P>0.05)。结论注射用亚胺培南西司他丁钠(齐佩能)治疗中重度细菌性感染疗效肯定且安全。更多还原

【Abstract】 Objective To evaluate the efficacy and safety of imipenem cilastatin sodium(Bacqure) in the treatment of moderate to severe bacterial infections.Methods A randomized controlled clinical trial was conducted.Imported imipenem cilastatin sodium(Tienam) was used as the control drug.Results The overall efficacy rate of Bacqure and Tienam was 86.42%and 81.82%respectively.The bacterial clearance rate was 85.71%and 87.18%respectively.The incidence rate of adverse reaction was 4.94%and 3.41%.There was no statistical significant difference between the two groups for the above results.Conclusion Imipenem cilastatin sodium(Bacqure) is a highly effective and safe antibacterial agent for the treatment of moderate to severe bacterial infections.更多还原