【摘要】 目的研究中药姜黄抗运动性疲劳效果及其作用机制。方法灌胃给予不同剂量姜黄30d后,进行小鼠爬杆实验、耐缺氧实验和大鼠骨骼肌收缩力学实验,并测定大鼠比目鱼肌超氧化物歧化酶(SOD)、丙二醛(MDA)和Ca2+-Mg2+-ATP酶活性。结果姜黄能明显延长小鼠爬杆时间、增强耐缺氧能力,可使大鼠骨骼肌收缩力增强,SOD和Ca2+-Mg2+-ATP酶活性增强、MDA值降低。结论姜黄在增加机体对运动负荷的适应能力、抵抗疲劳产生和加速疲劳消除方面具有明显的作用。更多还原

【Abstract】 Objective To investigate the anti-sports-fatigue effect of Chinese medicine curcuma longa and its mechanism. Methods Continuously pole climbing and anti-anoxia experiments were carried out on mice which were given with curcuma longa intragastrically at different doses for 30 days.The skeletal muscle contraction of rats and content of superoxide dismutase(SOD),malonaldehyde(MDA) and Ca2+-Mg2+-ATPase activity were detected. Results It was showed that curcuma longa obviously prolonged the time of climbing,raised anti-anoxia capability of mice,enforced the contraction of skeletal muscle and increased activities of Ca2+-Mg2+-ATPase and SOD,lowered the content of MDA. Conclusion Curcuma longa may have significant effect on the capability of adaptation to heavy exercise and prevention or elimination fatigue after exercise.更多还原