【摘要】 目的:探讨长期家庭氧疗联合夜间无创正压痛气(NIPPV)对稳定期慢性阻塞性肺疾病(COPD)患者预后的影响。方法:43例稳定期COPD患者随机分成两组,实验组(A组)采用家庭氧疗+夜间NIPPV+常规治疗(药物治疗+体育锻炼),对照组(B组)仅采用常规治疗,观察治疗前及治疗结束时两组患者的临床指标(住院天数、住院次数、就诊次数)、动脉血气、生活质量、肺功能的变化。结果:治疗后A组动脉血气、生活质量明显改善,A组肺功能无明显改善,B组肺功能明显下降,两组比较,差异有统计学意义(P<0.05或P<0.01)。A组住院天数、住院次数、就诊次数较B组明显减少。结论:长期家庭氧疗联合夜间NIPPV对改善稳定期COPD患者的预后有益。更多还原

【Abstract】 Objective:To discuss the impact of long-term oxygen therapy(LTOT) combined with noninvasive positive pressure ventilation(NIPPV) in night on the prognosis of patients with stable chronic obstructive pulmonary disease(COPD).Methods:43 patients with stable COPD were randomly divided into two groups, treatment group(group A) and control group(group B).Group A was given LTOT, NIPPV and conventional therapy(medication and exercise), and group B was only given conventional therapy.Then the clinical indicators(the frequency and numbers of days of hospitalization, the times to see the doctor), blood gas analysis, quality of life and lung function of the two groups were observed.Results:After treatment, the blood gas analysis and quality of life of group A were improved significantly, the lung function of group A showed no obvious change, but that of group B decreased significantly.The frequency and numbers of days of hospitalization and the times to see the doctor of group A were obviously reduced compared with those of group B.Conclusion:LTOT combined with NIPPV in night is benefit to improve the prognosis of patients with stable COPD.更多还原