【摘要】 目的:了解山西地区淋球菌对4种抗生素的耐药率及多重耐药现象,为临床用药提供实验依据。方法:采用纸片扩散法对110株淋球菌临床分离株进行青霉素、四环素、头孢曲松、环丙沙星四种药物敏感性测定。结果:耐青霉素、四环素、环丙沙星、头孢曲松的菌株分别占74.6%、81.8%、89.1%、0,同时耐2种及以上抗菌药物的多重耐药率为77.3%。结论:山西地区淋球菌青霉素、四环素及环丙沙星耐药率较高,已不宜用于淋病的治疗;头孢曲松几乎没有耐药现象,可以作为山西地区治疗淋病的首选药物。更多还原

【Abstract】 Objective: To evaluate the susceptibility of Neisseria gonorrhoeae to four antimicrobial agents in Shanxi. Methods:110 cases clinical isolates from patients with gonorrhoeae were collected.Disk diffusion method was used to test susceptibility of antimicrobial agents including penicillin, tetracycline, ceftriaxone, ciprofloxacin. Results: The positivity rates of resistant isolates to penicillin, tetracycline, ciprofloxacin, ceftriaxone were 74.6%, 81.8%, 89.1% and 0,positivity rates of multiple-resistantance isolates to four antimicrobial agents were 77.3%.Conclusion: The positivity rate to penicillin, tetracycline and ciprofloxacin increases rapidly. Ceftriaxone should be the first choice in the treatment of gonorrhes at present in Shanxi area.更多还原