【摘要】 目的:观察和胃散的急性毒性反应。方法:和胃散以最大浓度及最大给药体积的药液灌胃(ig)给药,3次/d。连续观察7d,记录小鼠毒副作用情况。结果:观察7d后,全部动物健存,小鼠体重平均增长24.82%,未见任何毒性作用。计算得和胃散最大给药量为54.0g/kg体重,相当于成人日用量的216倍。结论:本实验提示和胃散毒性较小。更多还原

【Abstract】 Objective: To study the toxic reaction of Hewei Powder in mice. Methods: The maximum administration dosage of Hewei Powder were determined by ig administration in mice, three times a day. Its acute toxic reactions were observed for 7 days. Results: All mice were survived, and no toxic reaction was shown during the observed period. The average rate of its increasing weight was 24. 82%. The maximum administration dosage was 54.0 g of Hewei Powder given to mice per kilogram, equivalent to men’s daily administration dosage by 216 times. Conclusion: Hewei Powder is safe for oral administration.更多还原