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非小细胞肺癌外周血微转移的研究现状

The Research Status of Micrometastasis of Non-small Cell Lung Cancer in Peripheral Blood

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【作者】 刘建; 任宏轩; 伍治平;

【Author】 LIU Jian,REN Hong-xuan,WU Zhi-ping.(The Third Affiliated Hospital of Kunming Medical College,the Second Department of Internal Medicine,Yunnan Oncology Hospital,Kunming 650118,China)

【机构】 昆明医学院第三附属医院; 云南省肿瘤医院内二科;

【摘要】 非小细胞肺癌(NSCLC)是常见的恶性肿瘤,治疗效果不佳,许多在术中证实为淋巴结阴性的患者仍在术后出现复发或转移的现象,这可能是常规的病理手段无法发现的微转移病灶所致。目前免疫组织化学和聚合酶链反应等技术已经应用于外周血、骨髓和肿瘤附近淋巴结中微转移灶的检测,然而微转移的检测指标的选择和临床意义仍未达成共识。

【Abstract】 Non-small cell lung cancer(NSCLC)is a common malignancy,with poor efficacy.Many patients who are proved to have no lymph node metastasis still suffer relapse after operation.The reason of this phenomenon may be that the means of conventional pathology cannot find micrometastatisis of the disease.At present,the immunocytochemistry and PCR methods were used to detect micrometastasis in the peripheral blood,bone marrow and lymph node.However,the selection and the clinical significance of micrometastasis index have not yet reached a consensus.

  • 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2009年23期
  • 【分类号】R734.2
  • 【被引频次】1
  • 【下载频次】106
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