【摘要】 采用器械的脊柱融合已成为治疗脊柱疾病的一种常用方法,包括特发性脊柱侧弯、椎体滑脱、椎管狭窄症的治疗。在体内,电化学作用、机械作用或两种作用一起引起的磨损和腐蚀,导致了金属的释放,从而引起局部和全身的反应。在脊柱旁的软组织内发现了金属颗粒碎片,主要为含铁的铁锈色颗粒,含铬的黑色颗粒和含钛的超细碎屑,这些碎片可导致一系列临床不良反应,如迟发性手术部位疼痛、骨质溶解。各种脊柱内置物置入机体以后,金属离子浓度显著升高,但金属离子浓度在临床实践中的意义还需要进一步研究。更多还原

【Abstract】 Spinal arthrodesis using instrumentation has become a common procedure to treat a variety of spinal disorders including idiopathic scoliosis,spondylolisthesis,spinal stenosis.In human body metals are released by electrochemical or mechanical mechanisms of corrosion and wear,or by their combination,and these factors are involved in local and systemic reaction.Metal debris has been found in the paraspinal soft tissues of patients with a variety of spinal instrumentation,which mainly include the rusty iron,the black chromium and the ultra-thin titanin.These particles may lead to a series of adverse clinical conditions such as late operative site pain and osteolysis.Elevated metalion concentrations were observed in subjects with a variety of spinal instrumentation,further studies should be designed to identify the useful metalion level in clinical practice.更多还原