【摘要】 目的探讨血清CA15-3测定在乳腺癌诊断、监测及术后复发转移中的临床应用价值。方法采用酶联免疫吸附法检测182例乳腺癌、85例乳腺良性疾病与100例正常健康体检女性的血清CA15-3水平。结果CA15-3在诊断乳腺良性疾病与乳腺癌Ⅰ,Ⅱ期时,差异无显著性(P>0.05),而在乳腺癌晚期及复发或转移乳腺癌患者中CA15-3水平显著高于无复发或无转移乳腺癌患者(P<0.05)。结论血清CA15-3监测乳腺癌的术后复发或转移、预测复发转移具有重要的意义。更多还原

【Abstract】 Objective To study the clinical value of serum CA15-3 determination in diagnosis,and monitoring postoperative recurrence and metastasis of breast cancer.Methods The enzyme-linked immunosorbent assay(ELISA) was used to detect CA15-3 in 182 patients with breast cancer,85 benign mammary disease and 100 control.Results The level of CA15-3 was no clearly different between benign mammary disease and breast cancer in stage I and II in combined application of CA15-3 detection(P>0.05);however it is significantly higher in the breast cancer patients with metastasis and recurrence than those who had no metastasis or recurrence(P<0.05).Conclusion Serum CA15-3 determination is very useful for monitor breast cancer and diagnose postoperative recurrence and metastasis in breast cancer.更多还原