【摘要】 目的探讨对手足口病(Hand,foot and mouth disease,HFMD)患儿心肌酶活性和C反应蛋白检测的意义,预防并发心肌炎的发生。方法以30例健康儿童作对照,对51例HFMD患儿进行心肌酶及C反应蛋白检测。结果手足口病患儿AST、LDH、CK、CK-MB、LDH-1、α-HBDH活性和CRP水平均高于正常对照组(P<0.05或P<0.01)。其中18例有心电图异常的病例,其心肌酶谱及CRP水平更是明显高于正常。结论部分手足口病患儿存在不同程度的心肌损害,心肌酶谱及C反应蛋白可作为手足口病患儿合并心肌损伤诊断依据和观察病情及判断预后的有效指标。更多还原

【Abstract】 Objective To evaluate the clinical significance of myocardial enzymes and C-reactive protein in the children with hand, foot and mouth disease(HFMD) and prevent myocarditis simultaneously. Methods Serum myocardial enzymes, excluding AST, LDH, CK, CK- MB, LDH-1, α-HBDH and CRP were examined in 51 cases with HFMD, and 30 healthy control group. Results The levels of serum myocardial enzymes and C-reactive protein, in the HFMD group including 18 cases with abnormal electrocardiogram were significantly higher than those in the control group (P<0.05 or P<0.01). Conclusion Different degree of myocardial injury existed in children with HFMD; myocardial enzymes and CRP could be used as a valuable marker for diagnosis, observing tendency, and predicting prognosis of myocardial injury in the children with HFMD.更多还原