【摘要】 综述有关干扰素导致抑郁症的潜在机制及预防与治疗的研究现状。干扰素是一组具有广谱抗病毒、抗肿瘤和免疫调节等多种生物活性的细胞因子,临床应用广泛,但其导致神经损伤、精神异常尤其是抑郁症的报道也不断增多,已引起研究者们的极大关注。更多还原

【Abstract】 The current status of researches on potential pathogenetic mechanism of interferon(IFN)-induced depression and its treatment and prevention was reviewed.IFNs,a group of cytokines showing multiple biological activities,such as broad-spectrum anti-virus,anti-tumor and immuno-modulation,have been widely used for clinic.However,IFN-induced depression reported more and more has aroused the interest of researchers.更多还原