【摘要】 目的:对不同企业的脑蛋白水解物注射液进行渗透压分析,为提高该品种的国家标准提供实验依据。方法:利用渗透压测定仪对国内32个生产厂家的103批脑蛋白水解物注射液进行测定。结果:脑蛋白水解物注射液渗透压在421～677mOsM之间,其中420～520mOsM有72批,占69.9%;521～600mOsM有28批,占27.2%;600mOsM以上的有3批,占2.9%。结论:国内不同厂家产品的渗透压差异较显著,有必要在脑蛋白水解物质量标准中增设渗透压检查项。更多还原

【Abstract】 Objective:The osmotic pressure of cerebroprotein hydrolysate injection was measured in order to improve its quality standard.Methods:The osmotic pressure of 103 batches of cerebroprotein hydrolysate injection from 32 pharmaceutical factories were measured on osmotic pressure analyzer.Results:The range of measured osmotic pressure of cerebroprotein hydrolysate injection was 421-677 mOsM.There were 72 batches(69.9% of 103 batches) which osmotic pressure fell within 420-520 mOsM,and 28 batches(27.2% of 103 batches) within 521-600 mOsM,and 3 batches(2.9% of 103 batches) with osmotic pressure of more than 600 mOsM.Conclusion:The difference of osmotic pressure from various pharmaceutical factories is obvious in some degree.It is necessary to test the osmotic pressure in the quality standard of cerebroprotein hydrolysate injection.更多还原