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金黄色葡萄球菌和凝固酶阴性的葡萄球菌红霉素诱导克林霉素耐药的检测

Staphylococcus aureus and coagulase-negative of clindamycin-induced aureus erythromycin resistance test

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【作者】 刘文秀齐学王晓静李春雷

【机构】 齐齐哈尔市中医医院

【摘要】 目的通过对齐市中医院临床分离葡萄球菌株中红霉素和克林霉素耐药性及红霉素诱导克林霉素的耐药发生率,为临床提供比较可靠的药敏结果。方法采用D试验检测280株葡萄球菌的可诱导克林霉素耐药性。结果红霉素和克林霉素均耐药占35%。D试验阳性占所测葡萄球菌的20.71%,占红霉素耐药克林霉素敏感株的70.73%。结论检测葡萄球菌属诱导型耐药,避免盲目使用克林霉素而导致治疗无效,帮助临床正确选用大环内酯类-林可酰胺类-链阳霉素B类(MLSB)抗菌药物。

【Abstract】 Objective Aceh Chinese medicine hospital clinical strains of Staphylococcus aureus isolated in erythromycin and clindamycin resistance induced by erythromycin and clindamycin resistance rate, in order to provide reliable clinical results of drug susceptibility.Methods D test of 280 can be induced aureus clindamycin resistance.Results erythromycin and clindamycin resistance were 35% . D test positive for Staphylococcus measured by accounting for 20.71 percent of the total erythromycin and clindamycin- resistant strains of the sensitive 70.73 percent. Conclusion The detection of an induced aureus resistant to avoid the blind use of clindamycin and lead to ineffective treatment to help choose the correct clinical macrolides - Lin lactam - Class B chain- yang (MLSB) anti- bacterial drug .

  • 【文献出处】 中国医疗前沿 ,China Healthcare Frontiers , 编辑部邮箱 ,2009年02期
  • 【分类号】R446.5
  • 【下载频次】76
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