【摘要】 作为环境类内分泌干扰物之一,双酚A由于被广泛作为化工原料使用而对环境和人类健康产生了严重的危害。文章对近年来国内外环境及生物样品中残留双酚A的最新前处理及检测技术的研究进展进行了综述。除常规前处理技术外,还介绍了包括搅拌棒吸附萃取及分子印迹等新型分离、富集技术在双酚A提取中的应用;另外,在着重介绍双酚A的色谱-质谱分析技术的基础上,对免疫分析、传感器检测和光学检测在双酚A检测中的应用也进行了详细报道。展望双酚A分析的发展趋势,二级串联质谱由于具有比其他分析方法更低的检出限,因此将会成为检测环境及生物样品中痕量双酚A的最具潜力的手段之一;研制价格低廉、重现性好、高通量的微型化、便携式、自动化仪器将是在线快速分析双酚A的另一个主要发展方向。更多还原

【Abstract】 As one of the environmental endocrine-disrupting chemicals,bisphenol A produces great harm to the environment and the human health due to its widespread use as the raw materials in chemical industry.This paper reviews the recent technical developments in the determination of trace bisphenol A in environmental and biological samples including sample separation,enrichment and analytical methods.Except for the regular sample pretreatment techniques,the applications of popular sample pretreatment technique such as stir bar sorptive extraction and molecular imprinting technique were also discussed.On the basis of the discussion on application of chromatography-mass spectrometry for bisphenol A analysis,the application of immunoassay,biosensor and optical detection techniques for bisphenol A analysis were also reported in detail.Finally,the trend in development of bisphenol A analysis techniques was prospected.The tandem mass spectrometry may be one of the potential analytical techniques for bisphenol A analysis due to its low detection limit.In addition,the minimized,portable and automated analyzer with characteristics of low price,good repeatability and high-throughput may be another development direction for the rapid analysis of bisphenol A.更多还原