【摘要】 目的:研究活力参软胶囊的抗缺氧作用。方法:用不同剂量的活力参软胶囊给正常小鼠连续灌胃30d,利用常压缺氧、亚硝酸钠中毒缺氧、急性断头脑缺氧动物模型测定其抗缺氧存活时间。结果:在小鼠常压缺氧实验中,活力参软胶囊中剂量(P<0.01)、高剂量(P<0.05)与溶媒组比较均能显著延长小鼠常压缺氧条件下的存活时间。在亚硝酸钠中毒实验中活力参低剂量(P<0.05)与溶媒组比较对延长小鼠存活时间作用明显。急性断头脑缺氧实验活力参中剂量(P<0.05)、高剂量(P<0.01)与溶媒组比较能显著延长小鼠存活时间。结论:活力参软胶囊具有显著的抗缺氧效果。更多还原

【Abstract】 Objective:To investigate the anti-hypoxia effects of Careseng RH.Methods:Mice were intragastric administrated with Careseng RH for 30 days,using normobaric hypoxia、sodium nitrite intoxication hypoxia、acute decapitation hypoxia models to determine the survival times of different groups.Results:In normobaric hypoxia test,Careseng RH medium(P<0.01) and high dose group(P<0.05) can significantly prolong the survival times compared with Solvent group;in sodium nitrite intoxication hypoxia test,low dose group(P<0.05) can prolong the survival times compared with Solvent group;in acute decapitation hypoxia test,medium(P<0.05) and high dose group(P<0.01) has the same effects compared with Solvent group.Conclusion:Careseng RH has notable anti-hypoxia effects.更多还原