【摘要】 以环十二酮为原料,经过α-取代反应生成中间体α-苯磺酰基环十二酮,先与NH2OH作用成肟然后酯化反应合成了20个未见文献报道的α-苯磺酰基环十二酮肟酯衍生物(8),其化学结构经1HNMR,IR和元素分析确证.初步生物活性测定结果显示,部分化合物具有一定的除草活性,如α-苯磺酰基环十二酮肟-2,4-二氯苯氧乙酸酯(8p)在浓度为100和1mg/L时对马唐(Digitaria sanguinalis)的抑制率分别为100%和80.07%;对苘麻(Abutilon theophrasti)的抑制率分别为100%和88.70%.毒力测定结果显示,8p对马唐的IC50值和苘麻的IC50值分别为0.192和0.151mg/L.更多还原

【Abstract】 Twenty novel compounds of α-phenylsulfonylcyclododecanone oxime esters (8) were synthesized by the acylation of α-phenylsulfonylcyclododecanone oxime. Their structures were confirmed by elemental analysis, 1H NMR, and IR spectral data. The preliminary bioassay results showed that α-phenyl-sulfonylcyclododecanone oxime 2,4-dichlorophenoxy acetate (8p) had inhibition ratio 100% and 80.07% against Digitaria sanguinalis (Linn.) Scop., and 100% and 88.70% against Abutilon theophrasti Medic. at concentrations of 100 and 1 mg/L. The IC50 for D. sanguinalis and IC50 for A. theophrasti of 8p were 0.192 and 0.151 mg/L, respectively.更多还原