【摘要】 目的研究不同颈总动脉生理流量波波形对颈动脉分叉壁面切应力的影响。方法建立颈动脉分叉TF-AHCB数值模型。用Womersley方法求解Bloch和Holdsworth两种经典的血液流量波形的速度分布,并作为入口条件用CFD软件计算分叉管内流场和壁面切应力分布。结果两种波形在颈动脉分叉根部外侧壁形成的低切应力区相仿,但具有较低重搏波波谷的Holdsworth波形使局部振荡剪切因子明显增大。Holdsworth波形产生的振荡剪切因子是Bloch波形产生的1.75倍,局部最高值可达0.49。结论在对动脉分叉管血流动力学数值或实验模拟中,正确设定入口流量波形和速度剖面条件是重要的。更多还原

【Abstract】 Objective To study the effect of different carotid artery flow waveform on the wall shear stress of carotid artery bifurcation. Method Special software is used to construct the carotid bifurcation TF-AHCB numerical model.Using Womersley method,two classic blood flow velocity profiles,Bloch and Holdsworth,were computed and inputted separately into CFD software as inlet conditions to compute the flow field and wall shear stress distribution of carotid artery bifurcation. Result Low wall shear stress zones of carotid artery bifurcation outboard root produced by the different flow waveforms are similar,but Holdsworth waveform makes oscillatory shear index increased significantly because of its lower dicrotic notch,and it is 1.75 times as the oscillatory shear index produced by Bloch and in some areas even high up to 0.49. Conclusions In carotid artery bifurcation hemodynamics numerical experiments or simulant experiments,correctly inlet flow waveform and velocity profile conditions are important.更多还原