【摘要】 脑血管疾病是一类严重危害人类健康的疾病,其中缺血性脑卒中占脑血管疾病的50%～80%。近年来研究表明,星型胶质细胞可通过维持胞外K+平衡,清除氧自由基,对神经元提供神经营养因子、摄取过量兴奋性氨基酸、调节离子通道等方式对脑缺血性疾病中的神经元提供保护作用。该综述就近年来星型胶质细胞在脑缺血性疾病中的神经元保护相关机制进行了阐述。更多还原

【Abstract】 Cerebral vascular diseases throw great threat to human health,among which ischemic stoke accounts for 50%~80%.Rencent results showed that astrocyte can protect the neurons during cerebral ischemia diseases via maintenance extracellular K+ homeostasis,elimination of oxygen free radicals,uptake the excess excitatory amino acid,release of neurotrophic factors and regulation the functions of ion channels.This article reviews the recently published works about the mechanisms of the neuroprotective effects of astrocyte during the cerebral ischemic diseases.更多还原