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宫康舒胶囊成型工艺研究

Research on formulation technique of Gongkangshu Capsule

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【作者】 陈昌利刘世琴王允

【Author】 CHEN Chang-li1,LIU Shi-qin2,Wang Yun3(1.Apitherapy Institute of Fujian Agricultureal Forestry University,Fuzhou,Fujian 350002,China;2.Tibetan Medicine Factory of Ritong Developing Center of Tibetan Medicine,Changdu,Tibet,854000;3.Chongqing University of Posts and Telecommunications,Chongqing 400065,China)

【机构】 福建农林大学蜂疗研究所昌都日通藏医药研制中心藏药厂重庆邮电大学

【摘要】 目的:探讨宫舒康胶囊的成型条件。方法:从辅料筛选、颗粒流动性、包装材料和包装环境的选择等几个方面进行考察。结果:测定所制颗粒的休止角为35.7度,堆密度为0.83g/ml,临界相对湿度为60%,筛选出辅料为淀粉,用量20%,选用1号胶囊进行装量。结论:本成型工艺颗粒流动性好,利于制粒。临界相对湿度在60%,比较可控。

【Abstract】 Objective:To establish the technique condition for formulating Gongkangshu Capsule.Methods:To take consideration of the filtration on adjuvant,the fluency of particles,package materials,and the packing environment.Results:The zero angle was 35.7,the bulk density was 0.83 g/ml,the critical relative humidity was 60%,and the adjuvant was chosen as starch at 20% of amount.Type 1 capsule was selected.Conclusion:The pharmaceutical technique chosen is superior in particle fluency and in granulation.The critical relative humidity was 60%,which is a relatively controllable level.

【关键词】 宫康舒胶囊成型工艺
【Key words】 GongkangshuCapsuleFormulationTechnology
  • 【文献出处】 现代医药卫生 ,Modern Medicine & Health , 编辑部邮箱 ,2009年08期
  • 【分类号】TQ461
  • 【被引频次】1
  • 【下载频次】135
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