【摘要】 目的:探讨食管胃底静脉曲张破裂出血(GEV)患者院内死亡事件的相关因素。方法:对因GEV入院患者的资料进行回顾性分析,研究相关的临床和实验室参数与患者院内死亡率的关系。结果:374例患者中有36例在院内死亡(占9.6%)。与存活患者相比,死亡患者的血清胆红素[44.5(18.8)vs25.7(8.6)μmol/L]、血清肌酐[203.3(123.8)vs97.2(44.2)μmol/L]水平及出现肝性脑病(PSE)的几率(50%vs20%)的差异具有统计学意义。死亡患者和存活患者内镜检查后24小时内再出血的发生率分别为44%和5%。结论:血清肌酐和胆红素水平、出现PSE及初次内镜治疗24小时内发生再出血是GEV患者死亡的相关因素。更多还原

【Abstract】 Objective:To investigate the factors related to in-hospital mortality in the patients with gastroesophageal variceal hemorrhage.Methods:The records of the in-patients with gastro esophageal variceal hemorrhage between January 2004 and December 2007 were retrospectively analyzed. The relevant clinical and laboratory parameters and their relationship to mortality were studied.Results:Of the 374 inpatients during the study period,36 (9.6%) died in hospital. Serum bilirubin [44.5(18.8)vs25.7(8.6)μmol/L] and serum creati- nine [203.3(123.8)vs97.2(44.2) μmol/L] levels were higher among non-survivors than among survivors. Non-survivors were also more likely to suffer from PSE (50%) than survivors(20%),while rebleeding within 24 h of endoscopy occurred in 44% and 5% of these groups,re- spectively. Conclusion:Serum creatinine and bilirubin levels,presence of PSE,and rebleeding within 24 h of initial endoscopy are related to mortality in the patients with gastro esophageal variceal bleeding.更多还原