【摘要】 目的探讨探究性眼动分析(EEM)与交感神经皮肤反应(SSR)对抑郁症患者的诊断价值。方法对42例抑郁症患者和40例正常健康者分别进行了EEM和SSR测定,并将结果加以比较。结果抑郁症组EEM和SSR的异常率分别为83%(35/42)和81%(34/42),二者异常一致率为76%(32/42)。抑郁症组EEM测定结果中凝视点(NEF)和反应探索评分(RSS)值均低于对照组,差异具有统计学意义(P<0.01),SSR波潜伏期和波幅值分别较对照组延长和降低,其差异具有统计学意义(P<0.01)。SSR波潜伏期与EEM测定中NEF、RSS呈负相关(r=-0.29～-0.36,P<0.01),SSR波幅与NEF、RSS呈正相关(r=0.32～0.33,P<0.01)。结论探究性眼动分析和交感神经皮肤反应测定可作为抑郁症患者的诊断指标应用于临床。更多还原

【Abstract】 Objective To explore the diagnostic value of exploratory eye movement(EEM)and sympathetic skin response(SSR)in patients with depression.Methods EEM and SSR test were used in forty-two depression patients and forty normal healthy people,and the results were compared between the two groups.Results The abnormal rate of EEM and SSR in depression group were 83%(35 /42)and 81%(34 /42) respectively,and the abnormal concordance rate was 76%(32 /42).The number of eye fixation(NEF)and the responsive search score(RSS) in depression group were significantly lower than those in control group(P < 0.01);The latency and the amplitude of SSR in depression group were significantly longer and lower than those in the control group(P < 0.01).Correlation analysis showed that there was a remarkable negative correlation with latency of SSR and NEF,RSS(r =-0.29 ～-0.36,P < 0.01),but there was positive correlation with amplitude of SSR and NEF,RSS(r =0.32 ～0.33,P < 0.01).Conclusion Exploratory eye movement and SSR test can be used as diagnostic indexes in patients with depression.更多还原