【摘要】 目的:探讨血清超敏C反应蛋白(hs-CRP)与心血管危险因素的关系。方法:对388例健康成人(男223例,女165例,年龄47～53岁)的身高、体重、血压、心电图、血糖、血脂及血清hs-CRP等进行测定。结果:由低至高的血清hs-CRP四等分组(<2.1mg/L,2.1～5.0mg/L,5.1～8.0mg/L,>8.0mg/L)的心血管危险因素体重指数、血压、空腹血糖、高密度脂蛋白-胆固醇(HDL-C)组间差异非常显著(F=7.63～22.46,P均<0.001),总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇(LDL-C)的组间差异有显著性(F=2.89～8.88,P分别为0.031,0.022,0.015),四组心血管危险因素聚集检出率分别为32.3%,48.9%,58.0%,79.4%,差异有显著性(x2=28.12,P<0.001)。结论:血清hs-CRP与心血管危险因素(体重指数、血压、血糖和血脂)有关。更多还原

【Abstract】 Objective:To study the associations of the serum high sensitive c-reactive protein(hs-CRP) with cardiovascular risk factors in Chinese normal adult population.Methods:Totally,388 adults(223 men and 165 women) aged 47～53 persons were divided into four groups according hs-CRP level(<2.1mg/L,2.1～5.0 mg/L,5.1～8.0 mg/L,>8.0 mg/L)and recorded in the study for clinic examinations involving anthropometry and measurements of blood pressure,fasting and 2 h plasma glucose and insulin levels,serum lipid profile and hs-CRP.Results:For the four groups according hs-CRP level,there were significant difference of cardiovascular risk factors [BMI,blood pressure,fasting plasma glucose levels,HDL-C(F=7.62～22.46,P<0.001 all)and TC,TG,LDL-C(F=2.89～8.88,P<0.05 all],and the rate of cluster of cardiovascular risk factors was 32.3%,48.9%,58.0%,79.4%(x2=28.12,P<0.001) from the lowest to the highest quartile of hs-CRP level respectively.Conclusion:There may be a significant relationship among hs-CRP and cardiovascular risk factors in the Chinese normal middle aged population.更多还原