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动脉粥样硬化免疫学防治进展

Atherosclerosis Prevention and Treatment Progress in Immunology

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【作者】 李小林李大主

【Author】 LI Xiao-lin1,LI Da-zhu2(1.Department of Cardiology,Xinzhou People’s Hospital,Wuhan 430400,China;2.Department of Cardiology,Union Hospital of Tongji Medical College,Huazhong University of Sciences and Technology,Wuhan 430022,China)

【机构】 武汉市新洲区人民医院心内科华中科技大学附属协和医院心内科

【摘要】 动脉粥样硬化所致的心、脑血管疾病是目前危害人类健康的首要疾病。1999年Ross提出了动脉粥样硬化是一种炎症性疾病的理论,近来这一理论逐渐被人们所认同,许多学者通过实验在动脉粥样硬化斑块中发现了许多活化的免疫细胞,并证实它们参与了动脉粥样硬化的发生和发展;另外,热休克蛋白60、氧化性低密度脂蛋白等还被认为是动脉粥样硬化的相关抗原,越来越多的实验正在深入地探讨动脉粥样硬化的免疫学防治,相关领域的研究正日益受到人们广泛的关注。

【Abstract】 The cardiac and cerebral vascular diseases caused by atherosclerosis are the primary diseases of present risks for human health.Ross proposed in 1999 atherosclerosis is an inflammatory disease of the theory,and this theory has gradually been recognized by many scholars,through experiments in the atherosclerotic plaque were found in much of activated immune cells and confirmed that atherosclerosis they participated in the occurrence and development;HSP60,ox-LDL has also been considered,such as the atherosclerosis-associated antigen,an increasing number of experiments is to go into the atherosclerosis immunological control,related areas of research are increasingly subject to a wide range of people concern.

  • 【文献出处】 心血管病学进展 ,Advances in Cardiovascular Diseases , 编辑部邮箱 ,2009年S1期
  • 【分类号】R543
  • 【被引频次】5
  • 【下载频次】545
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