【摘要】 目的:探讨胃肠道间质瘤(GIST)的多层螺旋CT征象与恶性分级的相关性。方法:回顾性分析64例胃肠道间质瘤的资料,所有病例均行多层螺旋CT平扫及增强扫描,并经病理免疫组织化学检查证实。结果:间质瘤以胃部多见,占62.50%(40/64),其次为小肠,占18.75%(12/64)。GIST多表现为类圆形实性,边界清楚(47/64),以外生性生长为主(32/64)。密度多不均匀,坏死(47/64)、溃疡(31/64)常见,以不均匀强化、延迟强化为主。肝脏和腹腔为主要转移部位,转移灶坏死常见,也呈延迟强化。11例GIST伴发其他肿瘤。GIST的部位、坏死与溃疡的存在、强化方式及转移灶的有无与恶性分级呈正相关(P<0.05)。结论:胃肠道间质瘤的螺旋CT表现具有一定特征,并且不均匀强化方式,CT图像上坏死与溃疡的检出、转移灶的出现以及发生部位有助于对恶性间质瘤的判定。更多还原

【Abstract】 Objective:To discuss the sign of gastrointestinal stromal tumors(GISTs)in spiral CT and to analysis its malignancy grade.Methods:Sixty-four cases of GISTs were analyzed retrospectively,all were checked by multi-slice spiral CT plain and enhancement scanning,and had immunity histochemistry confirmation.Results:The tumors were more in the stomach (40/64),the stomach body (n=16) and the fundus (n=11),and then in intestine (12/64).Most GIST were heterogeneous solid mass with clear boundary (47/64),exophytic growth (32/64),and always had necrosis (47/64) and ulcer (31/64),which had nonuniform strengthen,especially in delayed enhancement.Liver (11/13) and peritoneal (5/13) were the more likely metastatic sites.11 cases were accompanied with other tumors.GIST size,with necrosis and ulcer,non-uniform strengthen and had metastatic location had positive relationship with malignancy (P<0.05).Conclusion:GIST has some characteristic findings in Spiral CT.Some CT features maybe helpful in analysis of GIST malignancy grade.更多还原