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紫外分光光度法测定维甲酸软膏中维甲酸的含量
Determination of the tretinoin in the tretinoin ointment by UV
【摘要】 目的:建立维甲酸软膏的质量控制方法。方法:采用紫外分光光度法在336nm处测定维甲酸的含量。结果:维甲酸检测浓度在1.0~6.0μg/ml范围内与吸收度线性关系良好(r=0.9999),平均回收率为98.97%(RSD=0.80%)。结论:本法经济、安全。操作简便、快捷,重现性好,结果准确,适用于医院制剂的快速分析。
【Abstract】 Objective:Establish the UV method of tretinoin ointment quality control.Methods:We apply the UV spectrophotometry method with a wavelength of 336 nm.Results:The linear range of tretinoin were 1.0~6.0 μg/ml(r=0.999 9).The average recoveries of tretinoin ointment were 98.97%(RSD=0.80%).Conclusion:This method is reliable,accurate and suitable to apply in hospital.
- 【文献出处】 新疆医科大学学报 ,Journal of Xinjiang Medical University , 编辑部邮箱 ,2009年06期
- 【分类号】R927
- 【被引频次】4
- 【下载频次】105