【摘要】 [目的]通过对2005～2008年四川省钩端螺旋体病监测资料的分析,了解人群和宿主动物钩体菌群分布和变动情况,研究钩体病流行规律,为制定预防和控制措施提供依据。[方法]用显微镜凝集试验,对临床诊断病例、自然人群和宿主动物进行抗体测定。采集临床诊断病例血液和鼠、蛙、猪肾、牛中段尿,进行病原体分离培养。[结果]2005～2008年全省累计发生钩体病1316例,死亡11例,除攀枝花市、德阳市、甘孜州和阿坝州外,各市州均有病例报告。病人血清群以黄疸出血群为主,自然人群血清群以黄疸出血群和澳州群为主,宿主动物主要携带黄疸出血群钩体。[结论]近几年我省钩体病处于最低发病水平,主要宿主动物携带钩体菌群与病人感染主要菌群基本一致,主要流行菌群稳定。但培养分离出钩体的宿主动物主要为高山姬鼠,而不是黑线姬鼠。因此,钩体病监测仍不能放松,需密切注意主要传染源的变化。更多还原

【Abstract】 [Objective] To analyze the surveillance and survey data from 2008 to 2005 in Sichuan province,understand the distribution and movement of the leptospira serogroups in the crowd and the parasites,and provide basis for Leptospirosis prevention and control in Sichuan province.[Methods] Agglutination test was performed with a microscope to determine the clinical diagnosis cases,natural populations and reservoir host animal antibodies.Clinical diagnosis was performed to cases by collecting blood,mouse kidney and frog kidney and pig kidneys and water buffalo urine bovine,and pathogens were isolated and cultured.[Results] From 2005 to 2008,1316 cases of leptospirosis were occurred in Sichuan,including 11 cases of death.Cases were reported in all the cities except for Panzhihua,Deyang,Ganzi and Aba.Patients with icterohaemorrhagiae serogroups were the main carrieres.Serogroups of natural populations were mainly icterohaemorrhagiae serogroup and Australis serogroup.The reservoir host mainly carried icterohaemorrhagiae serogroup Leptospira.[Conclusion] Leptospirosis in recent years in our province showed a low level of incidence,The main reservoir host of leptospira serogroups were basically the same as the main leptospira serogroups of infected patients,and the major serogroups showed to be stable.However,taxonomic isolated Leptospira mainly from the Apodemus chevrieri,but not Apodemus agrarius.So monitoring Leptospirosis cannot relax,and closely attention should be paid to the changes in the main source of infection.更多还原