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山东省恶性肿瘤死亡率和构成比地区差异协方差矩阵主成分分析

PRINCIPLE COMPONENTS ANALYSIS WITH COVARIANCE MATRIX ON REGIONAL DIFFERENCES FOR MORTALITY AND PERCENTAGES OF CANCERS IN SHANDONG PROVINCE

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【作者】 郭晓雷孙建东马吉祥鹿子龙付振涛李维卡张吉玉徐爱强

【Author】 GUO Xiao-lei,SUN Jian-dong,MA Ji-xiang,et al.(Shandong Center for Disease Control and Prevention,Jinan 250014,China)

【机构】 山东省疾病预防控制中心山东大学公共卫生学院

【摘要】 [目的]利用主成分分析探讨山东省恶性肿瘤死亡的地区分布特征。[方法]利用SAS软件对山东省22个县市区2004~2006年的20种恶性肿瘤标化死亡率和构成比分别进行协方差矩阵主成分分析。[结果]前3个主成分就反映了总体差异90%以上的信息,其中仅第1主成分就提供了总体差异一半以上的信息。第1主成分主要反映了食管癌的地区差异,第2主成分主要反映肺癌的地区差异,兼顾胃癌和肝癌。各地区第1主成分得分呈现西高东低的趋势,根据第1和第2主成分可以将调查地区分为若干类别,表现为明显的地理聚集性。[结论]山东省各地区恶性肿瘤死亡的总体差异主要取决于少数高发肿瘤,包括食管癌、肺癌、胃癌、肝癌等,其中以食管癌地位最为突出。如能进一步扩大分析范围,可更好地查明恶性肿瘤死亡的地区特征。

【Abstract】 [Objective] To explore the characteristics of regional distribution of cancer deaths in Shandong Province with the principle components analysis.[Methods] The principle components analysis with covariance matrix for age-adjusted mortality rates and percentages of 20 types of cancer in 22 counties(cities) were carried out using SAS Software.[Results] Over 90% of the total information could be reflected by the top 3 principle components and the first principle component alone represented more than half of the overall regional variances.The first component mainly reflected the area differences of esophagus cancer.The second component mainly reflected the area differences of lung cancer,stomach cancer and liver cancer.The value of the first principal component scores showed a clear trend that the west areas possessed higher values and the east the lower values.Based on the top two components,the 22 counties(cities) could be divided into several geographical clusters.[Conclusion] The overall difference of regional distribution of cancers in Shandong is dominated by several major cancers including esophagus cancer,lung cancer,stomach cancer and liver cancer.Among them,esophagus cancer makes the largest contribution.If the range of counties(cities) analyzed could be further widened,the characteristics of regional distribution of cancer mortality would be better examined.

  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2009年11期
  • 【分类号】R73-31
  • 【下载频次】263
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