【摘要】 [目的]探讨喉癌发病的危险因素,以便制订相应的预防对策和措施。[方法]采用以医院和社区为基础的1︰2配比病例对照研究,对110例经病理学确诊的喉癌患者及220例对照的相关资料进行条件Logistic回归分析。[结果]有声嘶史、吸烟、饮酒、职业暴露、有癌症家族史是喉癌的危险因素,其OR值依次为5.530,4.128,4.062,26.000,14.156;摄食蔬菜是保护因素,OR值为0.182。[结论]为了降低喉癌的发病率,应多食蔬菜,戒烟限酒,减少职业暴露。更多还原

【Abstract】 [Objective] To investigate the risk factors of laryngeal carcinoma in Fujian,and provide science basis for for-mulating related intervention and measures.[Methods] 1︰2 matched case-control study were performed based on the hospital and community,and 110 patients with biopsy-proved laryngeal carcinoma and 220 controls were collected to analyze by condi-tional logistic regression.[Results] The history of hoarseness,smoking,drinking,occupation exposure and family history of cancer were independent risk factors of laryngeal carcinoma,and their ORs were 5.530,4.128,4.062,26.000,and 14.156,respectively.Vegetable consumption was an independent protect factor for laryngeal carcinoma.The OR was 0.182.[Conclu-sion] In order to decrease incidence of laryngeal carcinoma,people should eat more vegetables,stop smoking and drinking,and reduce occupational exposure.更多还原