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α-硫辛酸对2型糖尿病神经性足溃疡的疗效观察

OBSERVATION ON THE EFFECTS OF Α-LIPOIC ACID ON THE TREATMENT OF TYPE 2 DIABETIC NEUROPATHIC FOOT ULCER

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【作者】 夏威张菱文世林

【Author】 XIA Wei,ZHANG Ling,WEN Shi-lin.(Department of Endocrinology,the People’s Hospital of Henan Province,Zhengzhou 450003,China)

【机构】 河南省人民医院内分泌科

【摘要】 [目的]观察α-硫辛酸对糖尿病神经性足溃疡的疗效。[方法]随机选择28例2型糖尿病神经性足溃疡的患者,应用α-硫辛酸观察创面愈合情况,并与25例对照进行比较。[结果]α-硫辛酸组创面愈合总有效率96.4%高于对照组88.9%,差异有统计学意义(P﹤0.05)。[结论]α-硫辛酸可明显改善2型糖尿病神经性足溃疡。

【Abstract】 [Objective] To observe the therapeutic effect of α-lipoic acid on the treatment of diabetic neuropathic foot ul-cer.[Methods] 28 type 2 diabetic patients with neuropathic foot ulcers were randomly selected and treated with α-lipoic acid as well as compared to 25 patients in control group.[Results] The total healing rate of wound treated byα-lipoic acid was 96.4% which was significantly higher than that in control group with the rate of 88.9%(P﹤0.05).[Conclusion] α-lipoic acid could be an effective therapy in the treatment of type 2 diabetic neuropathic foot ulcer.

  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2009年04期
  • 【分类号】R587.2;R632.1
  • 【被引频次】1
  • 【下载频次】137
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