【摘要】 2001-08/2003-12南昌大学第一附属医院心胸外科分别为3例终末期心脏病患者进行了原位心脏移植,3例供者均为青年男性脑死亡者,供者与受者体质量差异均小于20%。3例受者均采用双腔静脉吻合法,移植后采用环孢素A、强的松及霉酚酸酯联合免疫抑制治疗。3例患者均顺利出院,心功能恢复至NYHAⅠ～Ⅱ级,围手术期无感染或严重排斥反应发生。提示良好的心肌保护、完善的围手术期处理以及合理的抗排斥治疗是心脏移植成功的关键。更多还原

【Abstract】 Three cases of terminal stage heart disease received orthotopic heart transplantation at the Department of Cardiothoracic Surgery,the First Hospital of Nanchang University between August 2001 and December 2003. These three cases were all female and died of brain death. Body weight difference between donor and recipient was less than 20%. All three cases underwent superior and inferior vena cave osculation and received immunosuppressive therapy of cyclosporine A,prednisone,and mycophenolate postoperatively. They were successfully discarded. Heart function recovered to grade I-Ⅱ(NYHA). No infection or serious rejection was found during the surgery. These results indicate that good donor heart preservation,consummate perioperative processing,and proper immunosuppressive therapy are the key measures of successful heart transplantation.更多还原